Description

6-tert-Butyl 2-Ethyl 4,5-Dihydro-3Ah-Pyrrolo[2,3-C]Pyridine-2,6(7H)-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused pyrrolopyridine structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting protein kinases and other enzymatic pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries via parallel and combinatorial synthesis to explore structure-activity relationships (SAR).
• API Development: Employed in the research and process development stages for new Active Pharmaceutical Ingredients (APIs), contributing to the core pharmacophore.
• Bioconjugation & Probe Synthesis: Its functional groups make it suitable for creating chemical probes and bioconjugates used in biochemical assays and diagnostic research.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process scale-up services for the global pharmaceutical industry.

Basic Information

Product Name	6-tert-Butyl 2-Ethyl 4,5-Dihydro-3Ah-Pyrrolo[2,3-C]Pyridine-2,6(7H)-Dicarboxylate
CAS No.	1135124-27-4
Molecular Formula	C17H26N2O4
Molecular Weight	322.40 g/mol
Synonyms	6-tert-Butyl 2-ethyl 4,5-dihydro-3aH-pyrrolo[2,3-c]pyridine-2,6(7H)-dicarboxylate; 2,6(7H)-Dicarboxylic acid, 4,5-dihydro-3aH-pyrrolo[2,3-c]pyridine-, 6-(1,1-dimethylethyl) 2-ethyl ester; Ethyl 6-tert-butyl-4,5-dihydro-3aH-pyrrolo[2,3-c]pyridine-2,6(7H)-dicarboxylate; tert-Butyl ethyl 4,5-dihydro-3aH-pyrrolo[2,3-c]pyridine-2,6(7H)-dicarboxylate; Pyrrolo[2,3-c]pyridine-2,6-dicarboxylate derivative; CAS 1135124-27-4
EINECS	Contact for details

Quality Control

Our 6-tert-Butyl 2-Ethyl 4,5-Dihydro-3Ah-Pyrrolo[2,3-C]Pyridine-2,6(7H)-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.