Description

5-Chloro-6-(Hydroxymethyl)-3-Pyridinecarboxylic Acid Methyl Ester (Ws204386) is a high-purity pyridine derivative building block essential for advanced organic synthesis. This compound matters as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and fine chemicals, where its unique chlorinated hydroxymethyl ester structure enables precise molecular construction. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly in medicinal chemistry research.
• Agrochemical Development: Used in the research and production of novel pesticides and herbicides, leveraging its pyridine core.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of high-value, complex organic molecules for various industrial applications.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chemical reactions in laboratory settings.

Basic Information

Product Name	5-Chloro-6-(Hydroxymethyl)-3-Pyridinecarboxylic Acid Methyl Ester (Ws204386)
CAS No.	1134777-22-2
Molecular Formula	C9H10ClNO3
Molecular Weight	215.63 g/mol
Synonyms	Methyl 5-chloro-6-(hydroxymethyl)nicotinate; 5-Chloro-6-(hydroxymethyl)-3-pyridinecarboxylic acid methyl ester; Ws204386; Methyl 5-chloro-6-(hydroxymethyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 5-chloro-6-(hydroxymethyl)-, methyl ester; Nicotinic acid, 5-chloro-6-(hydroxymethyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-(Hydroxymethyl)-3-Pyridinecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder/crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.