Description

5-((2S)(2-Piperidyl))-2-Chloropyridine is a high-purity chiral building block and advanced pharmaceutical intermediate of significant commercial and research interest. Its value lies in its defined stereochemistry and functionalized pyridine-piperidine scaffold, which is crucial for synthesizing bioactive molecules. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially for neurological and psychiatric disorders.
• Ligand Precursor: Used in the development of chiral ligands for asymmetric catalysis in fine chemical production.
• Agrochemical Research: Serves as a building block for creating new crop protection agents with specific activity.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Academic Research: Utilized in universities and research institutes for methodological development in organic synthesis and stereochemistry.

Basic Information

Product Name	5-((2S)(2-Piperidyl))-2-Chloropyridine
CAS No.	1134621-22-9
Molecular Formula	C10H13ClN2
Molecular Weight	196.68 g/mol
Synonyms	(2S)-2-(6-Chloropyridin-3-yl)piperidine; (S)-2-(6-Chloro-3-pyridinyl)piperidine; 2-Chloro-5-[(2S)-2-piperidinyl]pyridine; 5-[(2S)-Piperidin-2-yl]-2-chloropyridine; (S)-2-(6-Chloropyridin-3-yl)piperidine; 1134621-22-9; (S)-2-(6-Chloro-pyridin-3-yl)-piperidine
EINECS	Contact for details

Quality Control

Our 5-((2S)(2-Piperidyl))-2-Chloropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing full specifications, including enantiomeric excess (ee), is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.