Description

5-((2S)(2-Piperidyl))-2-Methoxypyridine CAS NO 1134621-21-8 is a chiral piperidine derivative and a key advanced pharmaceutical intermediate (API) with significant synthetic utility. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and process chemistry.

Application

• As a chiral building block in the synthesis of novel pharmaceutical candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Utilized as a key intermediate in the production of complex alkaloids and other bioactive natural product analogs.
• Employed in asymmetric catalysis and medicinal chemistry research for constructing stereogenic centers.
• Serves as a ligand precursor or a structural motif in the development of new chemical entities for agrochemical applications.
• Used in process development and scale-up activities for the commercial manufacturing of high-value fine chemicals.

Basic Information

Product Name	5-((2S)(2-Piperidyl))-2-Methoxypyridine
CAS No.	1134621-21-8
Molecular Formula	C11H16N2O
Molecular Weight	192.26 g/mol
Synonyms	(S)-5-(2-Piperidyl)-2-methoxypyridine; 2-Methoxy-5-[(2S)-2-piperidinyl]pyridine; 5-[(2S)-Piperidin-2-yl]-2-methoxypyridine; (S)-2-Methoxy-5-(piperidin-2-yl)pyridine; 5-((S)-2-Piperidyl)-2-methoxypyridine; 5-(2-Piperidinyl)-2-methoxypyridine (S-isomer); 1134621-21-8
EINECS	Contact for details

Quality Control

Our 5-((2S)(2-Piperidyl))-2-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity research and pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.