Description

Methyl 2-(4-Chloro-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Acetate CAS NO 1134327-80-2 is a high-value heterocyclic building block, specifically a functionalized pyrrolopyridine derivative, essential for advanced organic synthesis. This compound is critical for medicinal chemistry research and development, serving as a key precursor in the creation of novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities for therapeutic potential.
• Biochemical Tool Compound Synthesis: Employed in the preparation of specialized probes and inhibitors for studying cellular signaling mechanisms and enzyme functions.
• Fine Chemical Synthesis: Serves as a versatile intermediate for constructing complex heterocyclic frameworks found in agrochemicals and advanced materials.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	Methyl 2-(4-Chloro-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Acetate
CAS No.	1134327-80-2
Molecular Formula	C10H9ClN2O2
Molecular Weight	224.64 g/mol
Synonyms	Methyl (4-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)acetate; 4-Chloro-1H-pyrrolo[2,3-b]pyridin-3-ylacetic acid methyl ester; 3-Acetic acid, methyl ester, 4-chloro-1H-pyrrolo[2,3-b]pyridine; Methyl 2-(4-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)acetate; 4-Chloro-1H-pyrrolo[2,3-b]pyridine-3-acetic acid methyl ester; 1134327-80-2; 4-Chloro-3-(methoxycarbonylmethyl)-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our Methyl 2-(4-Chloro-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Acetate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.