Description

Methyl 2-(4-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Acetate is a high-value brominated heterocyclic building block, essential for advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate in the development of novel kinase inhibitors and other biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted small-molecule therapeutics, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery campaigns.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study specific biological pathways and protein functions.
• Agrochemical Research: Potential intermediate for developing new active ingredients with specific biological activity.
• Academic Research: Employed in universities and research institutes for methodological development in heterocyclic chemistry.
• Custom Synthesis: Building block for contract research organizations (CROs) and CDMOs producing specialized compounds for clients.

Basic Information

Product Name	Methyl 2-(4-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Acetate
CAS No.	1134327-78-8
Molecular Formula	C11H9BrN2O2
Molecular Weight	281.11 g/mol
Synonyms	4-Bromo-3-(2-methoxy-2-oxoethyl)-1H-pyrrolo[2,3-b]pyridine; Methyl (4-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)acetate; 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-3-(2-methoxy-2-oxoethyl)-; 4-Bromo-1H-pyrrolo[2,3-b]pyridine-3-acetic acid methyl ester; 1134327-78-8; Methyl 2-(4-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)acetate
EINECS	Contact for details

Quality Control

Our Methyl 2-(4-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full specifications are provided and can be tailored to meet specific client requirements for research or development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.