Description

1H-Pyrrolo[2,3-B]Pyridin-4-Amine, Hydrochloride (1:1) is a high-purity pharmaceutical intermediate and building block of significant importance in modern organic synthesis. This compound serves as a critical precursor in the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and other targeted therapeutic areas. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the discovery and synthesis of new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic frameworks.
• Chemical Biology: Employed in the development of molecular probes and tool compounds for studying biological pathways.
• Contract Manufacturing: Supplied to CDMOs for use in custom synthesis and scale-up projects under cGMP conditions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridin-4-Amine, Hydrochloride (1:1)
CAS No.	1134307-94-0
Molecular Formula	C7H8N3·HCl
Molecular Weight	169.62 g/mol (Free base); 206.07 g/mol (Hydrochloride salt)
Synonyms	4-Amino-1H-pyrrolo[2,3-b]pyridine hydrochloride; 1H-Pyrrolo[2,3-b]pyridin-4-amine hydrochloride; 4-Amino-7-azaindole hydrochloride; 7-Aza-4-aminoindole hydrochloride; 4-Amino-1H-pyrrolo[2,3-b]pyridine HCl; 1H-Pyrrolo[2,3-b]pyridin-4-amine HCl; 1134307-94-0
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridin-4-Amine, Hydrochloride (1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.