Description

3-Fluoro-2-(Pyrrolidin-1-Yl)Pyridine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a fluorine atom and a pyrrolidine moiety on a pyridine scaffold, enabling precise modulation of molecular properties for drug discovery. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It serves as a critical intermediate for constructing novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probe Development: Serves as a core structure for creating molecular probes to study biological pathways and protein functions.
• Process Chemistry & Scale-up: Utilized in route scouting and optimization for the commercial production of complex molecules.
• Library Synthesis for High-Throughput Screening: A valuable scaffold for generating diverse compound libraries in medicinal chemistry programs.

Basic Information

Product Name	3-Fluoro-2-(Pyrrolidin-1-Yl)Pyridine
CAS No.	1133115-40-8
Molecular Formula	C9H11FN2
Molecular Weight	166.20 g/mol
Synonyms	2-(Pyrrolidin-1-yl)-3-fluoropyridine; 3-Fluoro-2-(1-pyrrolidinyl)pyridine; 3-Fluoro-2-pyrrolidin-1-ylpyridine; 1133115-40-8; 3-Fluoro-2-pyrrolidinylpyridine; Pyridine, 3-fluoro-2-(1-pyrrolidinyl)-; 3-Fluoro-2-pyrrolidino pyridine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-(Pyrrolidin-1-Yl)Pyridine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid or powder
Identification (HPLC/GC)	Conforms
Identification (IR)	Conforms
Purity (HPLC/GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.