Description

2-Fluoro-5-(Thiophen-2-Yl)Pyridine is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both pyridine and thiophene rings with a strategic fluorine substituent, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in drug discovery and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its unique heterocyclic structure.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of advanced organic electronic materials, such as OLEDs and conductive polymers.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A valuable reagent for academic and industrial research exploring new fluorination reactions and heterocyclic chemistry.

Basic Information

Product Name	2-Fluoro-5-(Thiophen-2-Yl)Pyridine
CAS No.	1132832-80-4
Molecular Formula	C9H6FNS
Molecular Weight	179.21 g/mol
Synonyms	2-(5-Fluoropyridin-2-yl)thiophene; 5-(Thiophen-2-yl)-2-fluoropyridine; 2-Fluoro-5-(2-thienyl)pyridine; 2-Fluoro-5-thiophen-2-ylpyridine; Pyridine, 2-fluoro-5-(2-thienyl)-; 1132832-80-4; 2-Fluoro-5-(thiophene-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Thiophen-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.