Description

1-(5,6-Dichloropyridine-3-Carbonyl)Pyrrolidine-2-Carboxamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it provides a critical, structurally-defined building block essential for research and development in modern medicinal chemistry. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers targeting innovative therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Biochemical Tool Compound: Serves as a reference standard or a starting material for creating specialized probes in biological assays.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacology studies.

Basic Information

Product Name	1-(5,6-Dichloropyridine-3-Carbonyl)Pyrrolidine-2-Carboxamide
CAS No.	1132702-40-9
Molecular Formula	C11H9Cl2N3O2
Molecular Weight	286.11 g/mol
Synonyms	1-[(5,6-Dichloropyridin-3-yl)carbonyl]pyrrolidine-2-carboxamide; Pyrrolidine-2-carboxamide, 1-(5,6-dichloro-3-pyridinylcarbonyl)-; 5,6-Dichloro-N-(2-carbamoylpyrrolidin-1-yl)nicotinamide; 1132702-40-9; 1-(5,6-Dichloronicotinoyl)pyrrolidine-2-carboxamide
EINECS	Contact for details

Quality Control

Our 1-(5,6-Dichloropyridine-3-Carbonyl)Pyrrolidine-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.