Description

1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 5-Chloro-3-Iodo-, Ethyl Ester is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it provides a versatile and functionalized core structure for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides and pesticides due to its heterocyclic scaffold.
• Material Science: Acts as a building block for creating organic electronic materials and functional polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and bio-conjugates.
• Academic & Contract Research: Utilized in universities and CROs for methodological studies and exploring new chemical spaces.
• Custom Synthesis: A key starting material for contract manufacturing organizations (CMOs) producing bespoke fine chemicals for clients.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 5-Chloro-3-Iodo-, Ethyl Ester
CAS No.	1132610-98-0
Molecular Formula	C10H8ClIN2O2
Molecular Weight	350.54 g/mol
Synonyms	5-Chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester; Ethyl 5-chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 5-Chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-chloro-3-iodo-, ethyl ester; 1132610-98-0; 5-Chloro-3-iodo-ethyl pyrrolo[2,3-b]pyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 5-Chloro-3-Iodo-, Ethyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.