Description

Methyl 3-Bromo-4-Cyclopropylbenzoate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated benzoate ester structure with a cyclopropyl substituent. This compound is essential for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific steric and electronic properties into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, where the cyclopropyl group can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Precursor: Employed in the synthesis of organic electronic materials and liquid crystals due to its rigid, aromatic core.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Methyl 3-Bromo-4-Cyclopropylbenzoate
CAS No.	1131615-05-8
Molecular Formula	C11H11BrO2
Molecular Weight	255.11 g/mol
Synonyms	3-Bromo-4-cyclopropylbenzoic acid methyl ester; Methyl 3-bromo-4-cyclopropylbenzoate; Benzoic acid, 3-bromo-4-cyclopropyl-, methyl ester; 4-Cyclopropyl-3-bromobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-4-Cyclopropylbenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.