Description

Methyl 3-Iodo-4-(Trifluoromethoxy)Benzoate is a high-purity, multi-functional aromatic ester building block designed for advanced chemical synthesis. This compound is valued for its unique combination of iodine and trifluoromethoxy substituents, which are critical for modulating electronic properties and introducing structural diversity in target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and cross-coupling reactions, such as Suzuki-Miyaura couplings facilitated by the iodine substituent.
• Material Science: Employed in the synthesis of monomers and functionalized polymers with specific electronic or optical properties for advanced materials.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise functionalization on a benzoate core.

Basic Information

Product Name	Methyl 3-Iodo-4-(Trifluoromethoxy)Benzoate
CAS No.	1131614-65-7
Molecular Formula	C9H6F3IO3
Molecular Weight	346.04 g/mol
Synonyms	3-Iodo-4-(trifluoromethoxy)benzoic acid methyl ester; Methyl 3-iodo-4-(trifluoromethoxy)benzoate; Benzoic acid, 3-iodo-4-(trifluoromethoxy)-, methyl ester; Methyl 3-iodo-4-(trifluoromethoxy)benzenecarboxylate; 4-(Trifluoromethoxy)-3-iodobenzoic acid methyl ester; MFCD30533366
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Iodo-4-(Trifluoromethoxy)Benzoate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.