Description

(1-Piperidin-3-Yl-Azetidin-3-Yl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected heterocyclic amine building block of significant interest in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), especially within therapeutic areas targeting the central nervous system and other disease modalities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those containing fused piperidine-azetidine motifs.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing focused libraries and exploring structure-activity relationships (SAR) in drug discovery programs.
• Process Chemistry Development: Serves as a standardized building block for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands for asymmetric catalysis or metal complexes.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation.

Basic Information

Product Name	(1-Piperidin-3-Yl-Azetidin-3-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	1131594-78-9
Molecular Formula	C13H25N3O2
Molecular Weight	255.36 g/mol
Synonyms	tert-Butyl (1-(piperidin-3-yl)azetidin-3-yl)carbamate; 3-[3-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-azetidinyl]-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester; 1-BOC-3-(3-Piperidinyl)azetidin-3-amine; N-Boc-3-(3-piperidyl)azetidin-3-amine; (1-(Piperidin-3-yl)azetidin-3-yl)carbamic acid tert-butyl ester; BOC-Pip(Aze)-OH (contextual abbreviation)
EINECS	Contact for details

Quality Control

Our production of (1-Piperidin-3-Yl-Azetidin-3-Yl)-Carbamic Acid tert-Butyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We maintain ISO 9001 certified quality management systems, and material can be supplied under cGMP guidelines for advanced pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which can affect stability and handling. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.