Description

2-Amino-2-(3-Bromo-Phenyl)-Hexanoic Acid Methyl Ester is a high-purity, non-natural amino acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring both a bromoaryl group and a protected amino acid ester, makes it an invaluable intermediate for constructing complex molecules with high stereochemical control. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Peptidomimetics Synthesis: Used to incorporate non-proteinogenic amino acid residues into peptide chains to enhance stability, bioavailability, and biological activity.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators with specific modes of action.
• Ligand and Catalyst Development: Employed in the synthesis of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create labeled or modified amino acids for studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring specific brominated, aromatic amino acid derivatives.

Basic Information

Product Name	2-Amino-2-(3-Bromo-Phenyl)-Hexanoic Acid Methyl Ester
CAS No.	1131594-77-8
Molecular Formula	C₁₃H₁₈BrNO₂
Molecular Weight	300.19 g/mol
Synonyms	Methyl 2-amino-2-(3-bromophenyl)hexanoate; 2-(3-Bromophenyl)-2-aminohexanoic acid methyl ester; 3-Bromo-D-homophenylalanine methyl ester (related derivative); (3-Bromophenyl)norleucine methyl ester; α-Amino-3-bromohydrocinnamic acid, α-hexyl, methyl ester; L-2-Amino-2-(3-bromo-phenyl)-hexanoic acid methyl ester; (R/S)-2-Amino-2-(3-bromophenyl)hexanoic acid methyl ester; Methyl α-amino-3-bromobenzenehexanoate
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-2-(3-Bromo-Phenyl)-Hexanoic Acid Methyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) specifying purity (typically >97% by HPLC), chiral purity (when applicable), and impurity profiles is supplied with each shipment. Our quality commitment aligns with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or inert gas (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Specify enantiomer (R/S) upon request
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.