Description

5-Bromo-2-Ethylbenzoic Acid Ethyl Ester is a high-purity organic building block and ester derivative of benzoic acid, valued for its bromine and ethyl substituents which impart unique reactivity and steric properties. This compound is essential for synthetic chemists requiring a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D laboratories and production facilities engaged in the development of active pharmaceutical ingredients (APIs), liquid crystal materials, and advanced organic electronic compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, where the bromine atom serves as a handle for further functionalization.
• Liquid Crystal & OLED Materials: Acts as a precursor for creating specialized aromatic cores in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions to introduce the 2-ethylbenzoate moiety.
• Chemical Research & Development: Serves as a standard or reference material in analytical method development and pathway scouting.
• Material Science: Investigated for use in polymer modification and as a monomer for specialty polymers with specific optical or thermal properties.

Basic Information

Product Name	5-Bromo-2-Ethylbenzoic Acid Ethyl Ester
CAS No.	1131587-83-1
Molecular Formula	C11H13BrO2
Molecular Weight	257.13 g/mol
Synonyms	Ethyl 5-Bromo-2-ethylbenzoate; Benzoic acid, 5-bromo-2-ethyl-, ethyl ester; 2-Ethyl-5-bromobenzoic acid ethyl ester; 5-Bromo-2-ethyl-benzoic acid ethyl ester; Ethyl 5-bromo-2-ethylbenzoate; 1131587-83-1
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Ethylbenzoic Acid Ethyl Ester is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed impurity profiling available. Certificates of Analysis (COA) documenting lot-specific results for assay, related substances, and residual solvents are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.