Description

Ethyl 5-Bromo-2-(But-3-Enyl)Benzoate is a high-purity, synthetically valuable organic intermediate featuring a strategically positioned bromine atom and a terminal alkene functional group. This compound is essential for advanced organic synthesis, particularly in constructing complex molecular architectures via cross-coupling and cycloaddition reactions. It is primarily sought after by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, leveraging its bromine for Suzuki-Miyaura and other palladium-catalyzed cross-couplings.
• Agrochemical Research: Used in the development of new herbicides and fungicides, where the benzoate core and alkene group allow for structural diversification.
• Material Science: Serves as a monomer or precursor in the development of specialty polymers and liquid crystals.
• Organic Synthesis: Utilized in Diels-Alder reactions and other cycloadditions, exploiting the reactivity of the but-3-enyl side chain.
• Chemical Biology: Acts as a probe or linker in bioconjugation chemistry due to its orthogonal reactive handles (bromide and alkene).
• Catalyst Ligand Synthesis: Provides a framework for creating novel phosphine or nitrogen-based ligands for transition metal catalysis.

Basic Information

Product Name	Ethyl 5-Bromo-2-(But-3-Enyl)Benzoate
CAS No.	1131587-75-1
Molecular Formula	C₁₃H₁₅BrO₂
Molecular Weight	283.16 g/mol
Synonyms	5-Bromo-2-(but-3-en-1-yl)benzoic acid ethyl ester; Ethyl 5-bromo-2-(3-butenyl)benzoate; Benzoic acid, 5-bromo-2-(3-buten-1-yl)-, ethyl ester; 2-(But-3-en-1-yl)-5-bromobenzoic acid ethyl ester; 1131587-75-1; Ethyl 5-bromo-2-(but-3-enyl)benzoate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 5-Bromo-2-(But-3-Enyl)Benzoate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.