Description

Methyl 2-Iodo-5-Methoxy-[1,1'-Biphenyl]-4-Carboxylate is a high-purity, functionalized biphenyl derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as Suzuki-Miyaura cross-coupling reactions and as a precursor for active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those containing complex biaryl structures.
• Suzuki-Miyaura Cross-Coupling Reagent: The iodine substituent makes it an excellent electrophilic partner for palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific biphenyl scaffolds.
• Liquid Crystal & OLED Material Synthesis: Acts as a building block for creating advanced organic electronic materials due to its rigid, conjugated biphenyl core.
• Chemical Biology Probe Development: Utilized in the creation of molecular probes for studying biological pathways and protein interactions.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Methyl 2-Iodo-5-Methoxy-[1,1'-Biphenyl]-4-Carboxylate
CAS No.	1131587-53-5
Molecular Formula	C15H13IO3
Molecular Weight	368.17 g/mol
Synonyms	Methyl 2-iodo-5-methoxybiphenyl-4-carboxylate; 4'-Methoxy-2-iodo-[1,1'-biphenyl]-4-carboxylic acid methyl ester; 2-Iodo-5-methoxy-4'-carbomethoxybiphenyl; 2-Iodo-5-methoxybiphenyl-4-carboxylic acid methyl ester; Methyl 4'-methoxy-2-iodobiphenyl-4-carboxylate; Biphenyl-4-carboxylic acid, 2-iodo-5-methoxy-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Iodo-5-Methoxy-[1,1'-Biphenyl]-4-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.