Description

Ethyl 5-Iodo-2-Morpholinobenzoate is a high-purity organic building block featuring a benzoate ester core substituted with iodine and a morpholine ring. This compound matters as a versatile and critical intermediate in modern pharmaceutical research and fine chemical synthesis, enabling the construction of complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the preparation of advanced pesticide and herbicide molecules, leveraging the reactivity of the iodine substituent for further functionalization.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for constructing complex heterocyclic systems and functionalized aromatic compounds.
• Material Science Precursor: Potential intermediate in the synthesis of organic electronic materials, ligands for catalysts, or specialty polymers.
• Cross-Coupling Reactions: The aryl iodide moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck).
• Library Synthesis for Screening: Employed in combinatorial and parallel synthesis to create diverse compound libraries for biological activity screening.

Basic Information

Product Name	Ethyl 5-Iodo-2-Morpholinobenzoate
CAS No.	1131587-28-4
Molecular Formula	C13H16INO3
Molecular Weight	361.18 g/mol
Synonyms	Ethyl 5-iodo-2-morpholin-4-ylbenzoate; 2-Morpholino-5-iodobenzoic Acid Ethyl Ester; Benzoic acid, 5-iodo-2-morpholino-, ethyl ester; 4-(5-Iodo-2-(ethoxycarbonyl)phenyl)morpholine; Ethyl 5-iodo-2-(morpholin-4-yl)benzoate; 1131587-28-4; 5-Iodo-2-morpholinobenzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Iodo-2-Morpholinobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling and packaging are performed under controlled lighting conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.