Description

2,3-Dimethoxy-5-(Trimethylsilyl)Pyridine is a high-purity, functionalized pyridine derivative characterized by its unique trimethylsilyl and dimethoxy substituents. This compound serves as a versatile and valuable advanced pharmaceutical intermediate and key synthon in complex organic synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules, particularly in medicinal chemistry research and API development.
• Ligand and Catalyst Precursor: Used in the preparation of specialized ligands for transition metal catalysis and organometallic chemistry.
• Agrochemical Synthesis: Serves as a key intermediate in the production of advanced pesticides and herbicides.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Cross-Coupling Reactions: Acts as a substrate or reagent in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive trimethylsilyl group.
• Chemical Derivatization: Used for protecting group strategies and as a precursor for further functionalization in multi-step synthetic routes.

Basic Information

Product Name	2,3-Dimethoxy-5-(Trimethylsilyl)Pyridine
CAS No.	1131335-75-5
Molecular Formula	C10H17NO2Si
Molecular Weight	211.34 g/mol
Synonyms	5-(Trimethylsilyl)-2,3-dimethoxypyridine; 2,3-Dimethoxy-5-(trimethylsilyl)pyridine; Pyridine, 2,3-dimethoxy-5-(trimethylsilyl)-; 2,3-Dimethoxy-5-pyridyltrimethylsilane; TMS-Dimethoxypyridine
EINECS	Contact for details

Quality Control

Our 2,3-Dimethoxy-5-(Trimethylsilyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for purity and NMR for structural confirmation to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.