Description

2-Bromo-5-Iodo-3-Methoxypyridine is a high-purity halogenated pyridine derivative, a crucial building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought after by R&D chemists and process development scientists for applications in medicinal chemistry, material science, and the synthesis of specialized ligands.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drug candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science & OLED Development: Serves as a building block for creating electron-transport materials and ligands for metal-organic frameworks (MOFs) used in organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions due to the presence of both bromo and iodo substituents, allowing for selective functionalization.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized pyridine-based ligands for transition metal catalysis.
• Chemical Research & Development: A valuable tool compound in academic and industrial R&D labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Bromo-5-Iodo-3-Methoxypyridine
CAS No.	1131335-43-7
Molecular Formula	C6H5BrINO
Molecular Weight	313.92 g/mol
Synonyms	3-Methoxy-2-bromo-5-iodopyridine; 5-Iodo-2-bromo-3-methoxypyridine; 2-Bromo-5-iodo-3-pyridinol methyl ether; Pyridine, 2-bromo-5-iodo-3-methoxy-; 1131335-43-7
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Iodo-3-Methoxypyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and production applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system is designed to support customer needs for regulatory documentation and supply chain transparency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.