Description

tert-Butyl 5-Bromo-6-Chloro-3-Hydroxypyridin-2-Ylcarbamate is a high-purity, multi-functional pyridine derivative serving as a critical advanced pharmaceutical intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research and development.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring halogenated pyridine scaffolds.
• Agrochemical Research: Serves as a precursor for developing new pesticides, herbicides, and fungicides due to its halogenated structure.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and enzyme functions.
• Material Science: Potential monomer or precursor for synthesizing specialized polymers and organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development.

Basic Information

Product Name	tert-Butyl 5-Bromo-6-Chloro-3-Hydroxypyridin-2-Ylcarbamate
CAS No.	1131041-73-0
Molecular Formula	C10H12BrClN2O3
Molecular Weight	323.57 g/mol
Synonyms	tert-Butyl N-(5-Bromo-6-Chloro-3-Hydroxy-2-Pyridinyl)carbamate; 2-Pyridinecarboxamide, N-(5-bromo-6-chloro-3-hydroxy-2-pyridinyl)-, 1,1-dimethylethyl ester; 5-Bromo-6-chloro-3-hydroxypyridine-2-carboxylic acid tert-butylamide; Boc-Protected 5-Bromo-6-Chloro-3-Hydroxypyridin-2-amine; tert-Butyl (5-Bromo-6-Chloro-3-Hydroxy-2-Pyridyl)carbamate; 1131041-73-0; 2-((tert-Butoxycarbonyl)amino)-5-bromo-6-chloropyridin-3-ol
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Bromo-6-Chloro-3-Hydroxypyridin-2-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical-grade intermediates. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.