Description

Ethyl 2-Bromo-3-Fluorobenzoate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents, makes it a versatile intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated benzoate motifs.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated aromatic cores in electronic and photonic materials.
• Cross-Coupling Reactions: The bromine substituent acts as a handle for palladium-catalyzed reactions like Suzuki, Stille, or Negishi couplings to form biaryl structures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of tailored compounds for client-specific research programs.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological development in fluorination and esterification chemistry.

Basic Information

Item	Detail
Product Name	Ethyl 2-Bromo-3-Fluorobenzoate
CAS No.	1131040-49-7
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	2-Bromo-3-fluorobenzoic Acid Ethyl Ester; Ethyl 2-Bromo-3-fluorobenzoate; Benzoic acid, 2-bromo-3-fluoro-, ethyl ester; 3-Fluoro-2-bromobenzoic acid ethyl ester; Ethyl o-bromo-m-fluorobenzoate; 1131040-49-7; Ethyl 2-bromo-3-fluorobenzoate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2-Bromo-3-Fluorobenzoate is produced and tested under a strict quality management system. We guarantee high chemical purity and consistent lot-to-lot performance, supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.