Description

5-Bromo-2-(4-Methylpiperazin-1-Yl)Pyridine is a high-value pharmaceutical intermediate and versatile heterocyclic building block. This compound matters for its crucial role in the synthesis of complex molecules, particularly in medicinal chemistry for drug discovery and development. It is primarily needed by research institutions and pharmaceutical companies engaged in creating new active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly kinase inhibitors for oncology and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromine substituent.
• Agrochemical Development: Potential use as an intermediate in the research and synthesis of new crop protection agents and pesticides.
• Material Science Research: Can be utilized in the development of organic electronic materials and ligands for catalysis.

Basic Information

Product Name	5-Bromo-2-(4-Methylpiperazin-1-yl)pyridine
CAS No.	1130759-48-6
Molecular Formula	C10H14BrN3
Molecular Weight	256.14 g/mol
Synonyms	5-Bromo-2-(4-methyl-1-piperazinyl)pyridine; 2-(4-Methylpiperazin-1-yl)-5-bromopyridine; 5-Bromo-2-(4-methylpiperazin-1-yl)pyridine; 5-Bromo-2-(N-methylpiperazinyl)pyridine; 5-Bromo-2-(4-methylpiperazino)pyridine; 1130759-48-6; 5-Br-2-(4-Me-piperazin-1-yl)Py
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(4-Methylpiperazin-1-Yl)Pyridine is manufactured under strict quality management systems. We provide material with typical purity grades suitable for research and development, including standard and high-purity grades. All batches are characterized and tested to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (HPLC), identity (IR, NMR), and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade), ≥98.5% (High Purity Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.