Description

Ethyl 4-(Trifluoromethyl)-1,3-oxazole-5-carboxylate is a high-value fluorinated heterocyclic building block, essential for introducing the trifluoromethyl-oxazole pharmacophore into complex molecular architectures. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules with enhanced metabolic stability and lipophilicity. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new agrochemicals and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty polymers and functional materials that require fluorinated heterocyclic components.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Ethyl 4-(Trifluoromethyl)-1,3-oxazole-5-carboxylate
CAS No.	1126633-32-6
Molecular Formula	C7H6F3NO3
Molecular Weight	209.12 g/mol
Synonyms	Ethyl 4-(trifluoromethyl)oxazole-5-carboxylate; 5-Oxazolecarboxylic acid, 4-(trifluoromethyl)-, ethyl ester; 1,3-Oxazole-5-carboxylic acid, 4-(trifluoromethyl)-, ethyl ester; 4-(Trifluoromethyl)-1,3-oxazole-5-carboxylic acid ethyl ester; Ethyl 4-trifluoromethyloxazole-5-carboxylate; 4-Trifluoromethyl-oxazole-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to verify identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, providing batch-specific data. Our quality management system supports the needs of customers operating under cGMP and ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.