Description

1H-Pyrrolo[2,3-B]Pyridine-1-Carboxylic Acid, 4,6-Dichloro-, Methyl Ester is a high-purity, synthetically valuable heterocyclic building block. This compound is a critical intermediate in modern pharmaceutical research and development, particularly for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in medicinal chemistry programs targeting various disease areas.
• API Synthesis: Serves as a core scaffold or precursor in the multi-step synthesis of potential drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides due to its bioactive heterocyclic structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke chemical synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological development and novel heterocycle chemistry.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-1-Carboxylic Acid, 4,6-Dichloro-, Methyl Ester
CAS No.	1125592-35-9
Molecular Formula	C9H6Cl2N2O2
Molecular Weight	245.06 g/mol
Synonyms	4,6-Dichloro-1H-pyrrolo[2,3-b]pyridine-1-carboxylic acid methyl ester; Methyl 4,6-dichloro-1H-pyrrolo[2,3-b]pyridine-1-carboxylate; 4,6-Dichloro-1-(methoxycarbonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-1-carboxylic acid, 4,6-dichloro-, methyl ester; CAS 1125592-35-9
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-1-Carboxylic Acid, 4,6-Dichloro-, Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.