Description

5-(2-(Trifluoromethyl)Phenyl)Pyridine-3-Carboxamide is a high-value trifluoromethylated pyridine derivative, a key structural motif prized for its ability to modulate the physicochemical and metabolic properties of advanced molecules. This compound matters as a sophisticated pharmaceutical intermediate and research chemical, enabling the development of novel active ingredients with enhanced bioavailability and stability. It is primarily needed by R&D and process chemistry teams in the pharmaceutical, agrochemical, and advanced material sectors for the synthesis of targeted bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, receptor modulators, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl group can contribute to improved lipophilicity and biological activity.
• Material Science Precursor: Serves as a specialty monomer or ligand in the development of advanced organic electronic materials, metal-organic frameworks (MOFs), or functional polymers.
• Chemical Biology Probe: Employed in academic and industrial research to create molecular probes for studying enzyme function or biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	5-(2-(Trifluoromethyl)Phenyl)Pyridine-3-Carboxamide
CAS No.	1125421-92-2
Molecular Formula	C13H9F3N2O
Molecular Weight	266.22 g/mol
Synonyms	5-[2-(Trifluoromethyl)phenyl]pyridine-3-carboxamide; 5-(2-Trifluoromethylphenyl)nicotinamide; 3-Pyridinecarboxamide, 5-[2-(trifluoromethyl)phenyl]-; 1125421-92-2; 5-(2-(Trifluoromethyl)phenyl)nicotinamide; 5-(α,α,α-Trifluoro-o-tolyl)nicotinamide
EINECS	Contact for details

Quality Control

Our 5-(2-(Trifluoromethyl)Phenyl)Pyridine-3-Carboxamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.