Description

8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine is a high-value, heterocyclic organic building block featuring a fused triazolopyridine core with bromine and amine functional groups. This compound matters for its role as a versatile synthetic intermediate in advanced pharmaceutical research and agrochemical development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules, particularly in medicinal chemistry for hit-to-lead optimization.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and enzyme mechanisms.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Sonogashira, and Buchwald-Hartwig cross-coupling reactions.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries in high-throughput screening for drug discovery.

Basic Information

Product Name	8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
CAS No.	1124382-72-4
Molecular Formula	C6H4BrN5
Molecular Weight	226.03 g/mol
Synonyms	8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine; 2-Amino-8-bromo-[1,2,4]triazolo[1,5-a]pyridine; 8-Bromo-2-amino-[1,2,4]triazolo[1,5-a]pyridine; 1124382-72-4; 8-Bromo-2-aminotriazolopyridine
EINECS	Contact for details

Quality Control

Our 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for use under cGMP conditions for non-clinical research upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.