Description

Methyl 3-Bromo-5-Fluoro-4-Nitrobenzoate is a high-purity, multi-functional aromatic ester building block designed for advanced synthetic chemistry. This compound is valued for its precise molecular architecture, which incorporates bromo, fluoro, and nitro substituents on a benzoate core, enabling selective derivatization in complex reaction pathways. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting specific enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the reactivity of its halogen and nitro groups.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Chemical Synthesis: An essential building block for Suzuki-Miyaura, Buchwald-Hartwig, and other cross-coupling reactions to construct complex biaryl systems.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	Methyl 3-Bromo-5-Fluoro-4-Nitrobenzoate
CAS No.	1123171-93-6
Molecular Formula	C8H5BrFNO4
Molecular Weight	278.03 g/mol
Synonyms	3-Bromo-5-fluoro-4-nitrobenzoic acid methyl ester; Methyl 3-bromo-5-fluoro-4-nitrobenzoate; Benzoic acid, 3-bromo-5-fluoro-4-nitro-, methyl ester; Methyl ester of 3-bromo-5-fluoro-4-nitrobenzoic acid; 3-Bromo-5-fluoro-4-nitro methyl benzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Bromo-5-Fluoro-4-Nitrobenzoate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, IR). A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting cGMP and ISO 9001 quality management principles for reliable sourcing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound should be handled in accordance with good laboratory practices to prevent contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.