Description

3-Bromo-5-Methyl-2-(4H-1,2,4-Triazol-4-Yl)Pyridine (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic structure combining pyridine and triazole moieties. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for creating novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for synthesizing targeted small molecule candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization due to its bromine handle for further functionalization.
• Agrochemical Synthesis: Serves as a building block for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic processes.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	3-Bromo-5-Methyl-2-(4H-1,2,4-Triazol-4-Yl)Pyridine (Saltdata: Free)
CAS No.	1123169-57-2
Molecular Formula	C8H7BrN4
Molecular Weight	239.08 g/mol
Synonyms	3-Bromo-5-methyl-2-(4H-1,2,4-triazol-4-yl)pyridine; 2-(4H-1,2,4-Triazol-4-yl)-3-bromo-5-methylpyridine; 3-Bromo-5-methyl-2-(1,2,4-triazol-4-yl)pyridine; 1123169-57-2; 3-Bromo-5-methyl-2-(1H-1,2,4-triazol-1-yl)pyridine (tautomer); Pyridine, 3-bromo-5-methyl-2-(4H-1,2,4-triazol-4-yl)-; 4-(3-Bromo-5-methyl-2-pyridinyl)-4H-1,2,4-triazole
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Methyl-2-(4H-1,2,4-Triazol-4-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our standard grade meets research and development requirements, and we can support projects requiring ICH stability data or compliance with cGMP guidelines for advanced clinical stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.