Description

2,2,2-Trifluoro-n-(6-Fluoro-Imidazo[1,2-A]Pyridin-2-Yl)-Acetamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique fluorinated imidazopyridine scaffold. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical companies and research institutions focused on developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical development.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug candidate potency, selectivity, and metabolic stability.
• Fluorinated Compound Library Synthesis: Serves as a valuable precursor for creating diverse chemical libraries targeting various biological pathways.
• Kinase Inhibitor Development: The imidazopyridine core is a privileged structure in the design of kinase inhibitors for cancer therapy.
• CNS Drug Discovery: Applied in the research of novel compounds for neurological and psychiatric disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug development pipelines.

Basic Information

Product Name	2,2,2-Trifluoro-n-(6-Fluoro-Imidazo[1,2-A]Pyridin-2-Yl)-Acetamide
CAS No.	1123163-33-6
Molecular Formula	C9H5F4N3O
Molecular Weight	247.15 g/mol
Synonyms	2,2,2-Trifluoro-N-(6-fluoroimidazo[1,2-a]pyridin-2-yl)acetamide; 6-Fluoro-2-(2,2,2-trifluoroacetamido)imidazo[1,2-a]pyridine; 2-Acetamide, 2,2,2-trifluoro-N-(6-fluoroimidazo[1,2-a]pyridin-2-yl)-; N-(6-Fluoroimidazo[1,2-a]pyridin-2-yl)-2,2,2-trifluoroacetamide; CAS 1123163-33-6; 1123163-33-6; 6-Fluoro-2-(trifluoroacetamido)imidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-n-(6-Fluoro-Imidazo[1,2-A]Pyridin-2-Yl)-Acetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support development projects requiring material that meets stringent ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.