Description

2-Boc-7-Formyl-1,2,3,4-Tetrahydropyrrolo[3,2,1-Jk][1,4]Benzodiazepine is a high-purity, advanced pharmaceutical intermediate with a protected amine functionality. This compound is critical for the synthesis of novel therapeutic agents, particularly in the field of central nervous system (CNS) drug discovery and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the creation of new benzodiazepine-derived active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of proprietary benzodiazepine-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new compounds targeting GABA receptors.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target molecules.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for the production of clinical trial materials and non-commercial APIs.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	2-Boc-7-Formyl-1,2,3,4-Tetrahydropyrrolo[3,2,1-Jk][1,4]Benzodiazepine
CAS No.	1122597-86-7
Molecular Formula	C19H22N2O3
Molecular Weight	326.39 g/mol
Synonyms	7-Formyl-2-[(tert-butoxy)carbonyl]-1,2,3,4-tetrahydropyrrolo[3,2,1-jk][1,4]benzodiazepine; tert-Butyl 7-formyl-1,2,3,4-tetrahydropyrrolo[3,2,1-jk][1,4]benzodiazepine-2(1H)-carboxylate; 2-Boc-7-formyl-THP-BDZ; 2-(tert-Butoxycarbonyl)-7-formyl-1,2,3,4-tetrahydropyrrolo[3,2,1-jk][1,4]benzodiazepine; 1122597-86-7
EINECS	Contact for details

Quality Control

Our production of 2-Boc-7-Formyl-1,2,3,4-Tetrahydropyrrolo[3,2,1-Jk][1,4]Benzodiazepine adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. All materials are characterized by modern analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.