Description

Sulfo Cy3 Carboxylic Acids(Methyl) CAS NO 1121756-11-3 is a key intermediate in the synthesis of water-soluble cyanine dye conjugates, offering enhanced stability and solubility for advanced labeling applications. Its primary value lies in providing a reactive carboxylic acid group for covalent attachment to biomolecules, while the sulfonate group ensures excellent aqueous compatibility, reducing aggregation and non-specific binding. This compound is essential for researchers and manufacturers in the life sciences, diagnostics, and pharmaceutical development sectors who require high-performance fluorescent probes for imaging, flow cytometry, and in vitro assays.

Application

• Fluorescent Labeling of Biomolecules: Conjugation to antibodies, proteins, peptides, and oligonucleotides for detection and quantification.
• Bioimaging and Microscopy: Synthesis of cell-permeable probes for live-cell and fixed-cell imaging applications.
• Flow Cytometry Reagent Development: Creation of bright, photostable dyes for multicolor panel design in immunophenotyping.
• In Vitro Diagnostics (IVD): Component in the manufacture of fluorescent lateral flow assays and ELISA kits.
• Drug Discovery & High-Throughput Screening (HTS): Tagging of small molecules or targets in binding and activity assays.
• Nucleic Acid Detection: Labeling of probes for fluorescence in situ hybridization (FISH) and real-time PCR.

Basic Information

Product Name	Sulfo Cy3 Carboxylic Acids(Methyl)
CAS No.	1121756-11-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Sulfo-Cyanine3 carboxylic acid, methyl ester; Sulfo Cy3 ME; Water-soluble Cy3 acid methyl ester; 2-((1E,3E)-5-((E)-1-(5-Carboxypentyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indol-1-ium-5-sulfonate methyl ester; Cyanine3 sulfonated carboxylic acid methyl ester; Sulfo-Cy3-COOH(Me); Fluorescent dye intermediate Sulfo Cy3
EINECS	Contact for details

Quality Control

Our Sulfo Cy3 Carboxylic Acids(Methyl) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the high standards required for sensitive life science applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and performance characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	Dark red to purple solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.