Description

3-[(4-Methylbenzyl)Oxy]Azetidine is a specialized organic building block featuring an azetidine ring functionalized with a 4-methylbenzyloxy substituent. This compound matters as a high-value intermediate in modern pharmaceutical and agrochemical research, enabling the synthesis of novel molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and crop protection industries for constructing complex nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the azetidine scaffold for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Material Science: Potential monomer or additive in the development of advanced polymers with specific thermal or mechanical properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-[(4-Methylbenzyl)Oxy]Azetidine
CAS No.	1121633-97-3
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	3-[(4-Methylphenyl)methoxy]azetidine; 3-(p-Tolylmethoxy)azetidine; Azetidine, 3-[(4-methylbenzyl)oxy]-; 1-Azetidinyloxy(4-methylphenyl)methane; 3-(4-Methylbenzyloxy)azetidine; 3-O-(4-Methylbenzyl)azetidine; p-Methylbenzyl azetidin-3-yl ether
EINECS	Contact for details

Quality Control

Our 3-[(4-Methylbenzyl)Oxy]Azetidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for advanced intermediates intended for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.