Description

2-Amino-5-Chloropyridin-4-Ol is a high-purity, versatile pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique bifunctional structure, featuring both amino and hydroxyl groups on a chlorinated pyridine core, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used to create chelating ligands for metal catalysis and coordination chemistry applications.
• Material Science: Monomer or functionalizing agent in the production of specialty polymers and advanced organic electronic materials.
• Chemical Research: Versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Industry: Intermediate in the manufacture of complex heterocyclic dyes and colorants.

Basic Information

Product Name	2-Amino-5-Chloropyridin-4-Ol
CAS No.	1121585-12-3
Molecular Formula	C5H5ClN2O
Molecular Weight	144.56 g/mol
Synonyms	4-Hydroxy-2-amino-5-chloropyridine; 5-Chloro-2-amino-4-pyridinol; 2-Amino-5-chloro-4-hydroxypyridine; 5-Chloro-4-hydroxy-2-aminopyridine; 2-Amino-5-chloro-4(1H)-pyridinone; 5-Chloro-2-amino-4(1H)-pyridone; 2-Amino-5-chloro-4-pyridone; 5-Chloro-4-pyridinol-2-amine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for 2-Amino-5-Chloropyridin-4-Ol, ensuring batch-to-batch consistency and high purity suitable for demanding synthetic applications. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with comprehensive testing for identity, residual solvents, and related substances. A Certificate of Analysis (COA) documenting all test results is provided with every shipment, and we support custom purity requirements for pharmaceutical (GMP) or research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.