Description

2-(7-(Trifluoromethyl)Chroman-4-Yl)Acetic Acid is a high-value fluorinated chroman derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring a trifluoromethyl group on the aromatic ring, is engineered to impart enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is utilized to construct novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science Precursor: Serves as a monomer or functional additive in the synthesis of specialty polymers and advanced organic materials.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and target identification.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	2-(7-(Trifluoromethyl)Chroman-4-Yl)Acetic Acid
CAS No.	1121583-64-9
Molecular Formula	C₁₂H₁₁F₃O₃
Molecular Weight	260.21 g/mol
Synonyms	2-[7-(Trifluoromethyl)-3,4-dihydro-2H-chromen-4-yl]acetic acid; 2-[7-(Trifluoromethyl)-3,4-dihydro-2H-1-benzopyran-4-yl]acetic acid; 2-(7-(Trifluoromethyl)chroman-4-yl)ethanoic acid; 4-Carboxymethyl-7-trifluoromethylchroman; 7-(Trifluoromethyl)chroman-4-ylacetic Acid; 1121583-64-9; 2-(7-(Trifluoromethyl)-3,4-dihydro-2H-chromen-4-yl)acetic acid
EINECS	Contact for details

Quality Control

Our production of 2-(7-(Trifluoromethyl)Chroman-4-Yl)Acetic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We operate under a cGMP-compliant quality system to guarantee reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.