Description

5-Nitro-3-(trifluoromethyl)-2-pyridinamine is a high-purity, functionalized pyridine derivative of significant interest in advanced chemical synthesis. This compound matters as a key building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique trifluoromethyl and nitro-substituted amine structure enables precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Serves as a key scaffold for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Used in the research and development of advanced functional materials, including liquid crystals and organic electronic components.
• Chemical Synthesis: Acts as a versatile building block for creating complex heterocyclic compounds and fluorinated molecules in academic and industrial R&D settings.
• Bioconjugation & Probe Development: Utilized in the design of chemical probes and bioconjugation reagents for biochemical and diagnostic applications.

Basic Information

Product Name	5-Nitro-3-(trifluoromethyl)-2-pyridinamine
CAS No.	1121056-94-7
Molecular Formula	C6H4F3N3O2
Molecular Weight	207.11 g/mol
Synonyms	2-Amino-5-nitro-3-(trifluoromethyl)pyridine; 3-(Trifluoromethyl)-5-nitro-pyridin-2-ylamine; 5-Nitro-3-trifluoromethylpyridin-2-amine; 2-Pyridinamine, 5-nitro-3-(trifluoromethyl)-; 5-Nitro-3-(trifluoromethyl)pyridin-2-amine
EINECS	Contact for details

Quality Control

Our 5-Nitro-3-(trifluoromethyl)-2-pyridinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.