Description

6-Bromo-8-Trifluoromethyl-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is critical for research and development in the pharmaceutical and agrochemical sectors, where its unique trifluoromethyl and bromo substituents enable the creation of novel bioactive molecules. It serves as a key intermediate for medicinal chemists and process development scientists seeking to introduce specific halogenated and fluorinated motifs into target structures.

Application

This specialized intermediate is engineered for high-value synthesis in regulated industries. Its primary applications include:

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science Precursor: Serves as a starting material for creating advanced organic electronic materials and liquid crystals.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	6-Bromo-8-Trifluoromethyl-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid
CAS No.	1121051-31-7
Molecular Formula	C9H4BrF3N2O2
Molecular Weight	309.04 g/mol
Synonyms	6-Bromo-8-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid; 2-Imidazo[1,2-a]pyridinecarboxylic acid, 6-bromo-8-(trifluoromethyl)-; 1121051-31-7; 6-Bromo-8-trifluoromethylimidazo[1,2-a]pyridine-2-carboxylic acid; Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-bromo-8-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 6-Bromo-8-Trifluoromethyl-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.