Description

3,5-Dimethoxy-n-{2-[3-(3-Pyridinyl)-1,2,4-Oxadiazol-5-Yl]Phenyl}Benzamide is a high-purity, non-nucleoside reverse transcriptase inhibitor (NNRTI) intermediate of significant interest in advanced pharmaceutical research and development. This compound matters for its critical role as a key building block in the synthesis of next-generation antiviral therapeutics, particularly those targeting HIV. Pharmaceutical companies, biotechnology research firms, and advanced contract development and manufacturing organizations (CDMOs) require this specific intermediate to ensure the integrity and efficacy of their final active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of novel non-nucleoside reverse transcriptase inhibitor (NNRTI) drug candidates for antiviral therapies.
• Antiviral Drug Development: Key precursor in research programs focused on HIV-1 and other retroviral infections, enabling structure-activity relationship (SAR) studies.
• Biochemical Research: Used as a reference standard and probe compound in enzymatic assays to study reverse transcriptase inhibition mechanisms.
• Contract Manufacturing: Supplied to CDMOs for scale-up synthesis under cGMP conditions for clinical trial material and commercial API production.
• Academic Research: Utilized in university and institutional laboratories for medicinal chemistry projects exploring heterocyclic compounds with biological activity.

Basic Information

Product Name	3,5-Dimethoxy-n-{2-[3-(3-Pyridinyl)-1,2,4-Oxadiazol-5-Yl]Phenyl}Benzamide
CAS No.	1120266-48-9
Molecular Formula	C22H18N4O4
Molecular Weight	402.41 g/mol
Synonyms	3,5-Dimethoxy-N-[2-[3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl]phenyl]benzamide; Benzamide, 3,5-dimethoxy-N-[2-[3-(3-pyridinyl)-1,2,4-oxadiazol-5-yl]phenyl]-; NNRTI Intermediate 1120266-48-9; 1,2,4-Oxadiazole Benzamide Derivative; 3-Pyridinyl Oxadiazole Benzamide
EINECS	Contact for details

Quality Control

Our 3,5-Dimethoxy-n-{2-[3-(3-Pyridinyl)-1,2,4-Oxadiazol-5-Yl]Phenyl}Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC, to ensure compliance with research and pharmaceutical-grade standards. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.