Description

6-Ethyl-1-(2-Fluorophenyl)-3-Methyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyridine class of heterocyclic compounds. Its core value lies in its role as a critical building block for the synthesis of novel, targeted therapeutic agents, particularly in oncology and antiviral research. This compound is essential for medicinal chemistry R&D teams and pharmaceutical manufacturers engaged in developing small-molecule drugs, where precise chemical structure and batch-to-batch consistency are paramount for successful clinical outcomes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Oncology Research: Serves as a scaffold for developing kinase inhibitors and other targeted cancer therapies.
• Antiviral Drug Development: Used in research programs aimed at creating novel antiviral compounds.
• Medicinal Chemistry & SAR Studies: Employed for structure-activity relationship (SAR) optimization to enhance drug potency and selectivity.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for cGMP-scale production.
• Biochemical Research: Used as a reference standard or probe in biochemical assays to study specific biological pathways.

Basic Information

Product Name	6-Ethyl-1-(2-Fluorophenyl)-3-Methyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1119499-72-7
Molecular Formula	C₁₈H₁₆FN₃O₂
Molecular Weight	325.34 g/mol
Synonyms	1-(2-Fluorophenyl)-6-ethyl-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 6-Ethyl-1-(2-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 6-ethyl-1-(2-fluorophenyl)-3-methyl-; 1119499-72-7; 6-Ethyl-1-(2-fluorophenyl)-3-methylpyrazolo[3,4-b]pyridine-4-carboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 6-ethyl-1-(2-fluorophenyl)-3-methyl-
EINECS	Contact for details

Quality Control

Our 6-Ethyl-1-(2-Fluorophenyl)-3-Methyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The material may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.