Description

Methyl {[2-Chloro-4-(Trifluoromethyl)Phenyl]Thio}Acetate is a high-value organosulfur and organofluorine building block used in advanced chemical synthesis. This compound matters for its unique molecular architecture, combining a thioether linkage with a trifluoromethylphenyl group, which is critical for modulating the physicochemical properties of target molecules. It is primarily needed by R&D and production chemists in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in protease inhibitor and kinase inhibitor research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the CF3 group enhances bioavailability and environmental stability.
• Material Science Research: Serves as a precursor for specialty monomers and ligands in catalyst systems.
• Custom Synthesis & Contract Manufacturing: A critical starting material for bespoke chemical synthesis services targeting complex, fluorinated molecules.
• Academic & Industrial R&D: Employed in discovery chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	Methyl {[2-Chloro-4-(Trifluoromethyl)Phenyl]Thio}Acetate
CAS No.	1119451-07-8
Molecular Formula	C10H8ClF3O2S
Molecular Weight	284.68 g/mol
Synonyms	Methyl (2-chloro-α,α,α-trifluoro-p-tolylthio)acetate; Methyl [2-chloro-4-(trifluoromethyl)phenylthio]acetate; Methyl 2-((2-chloro-4-(trifluoromethyl)phenyl)thio)acetate; Acetic acid, 2-[(2-chloro-4-(trifluoromethyl)phenyl)thio]-, methyl ester; 1119451-07-8; Methyl (2-chloro-4-trifluoromethylphenylthio)acetate; Methyl 2-(2-chloro-4-(trifluoromethyl)phenylthio)acetate
EINECS	Contact for details

Quality Control

Our production of Methyl {[2-Chloro-4-(Trifluoromethyl)Phenyl]Thio}Acetate adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.