Description

5-(4-Bromophenyl)-2-Chloropyridine-3-Carboxaldehyde is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in pharmaceutical and agrochemical research and development. This compound is essential for medicinal chemists and process development scientists working on the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a building block for creating organic ligands in catalysis and for synthesizing advanced polymers with specific electronic properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of molecular probes and tags.
• Academic & Contract Research: A valuable reagent for methodology development and exploring new chemical spaces in university and CRO laboratories.
• Custom Synthesis & Scale-Up: The foundational material for contract manufacturing organizations (CMOs) performing custom synthesis and process optimization for client projects.

Basic Information

Product Name	5-(4-Bromophenyl)-2-Chloropyridine-3-Carboxaldehyde
CAS No.	1119449-39-6
Molecular Formula	C12H7BrClNO
Molecular Weight	296.55 g/mol
Synonyms	2-Chloro-5-(4-bromophenyl)pyridine-3-carboxaldehyde; 3-Formyl-2-chloro-5-(4-bromophenyl)pyridine; 5-(4-Bromophenyl)-2-chloro-3-pyridinecarboxaldehyde; 2-Chloro-5-(p-bromophenyl)nicotinaldehyde; 5-(4-Bromophenyl)-2-chloronicotinaldehyde; (2-Chloro-5-(4-bromophenyl)pyridin-3-yl)methanal
EINECS	Contact for details

Quality Control

Our 5-(4-Bromophenyl)-2-Chloropyridine-3-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.