Description

2-Chloro-5-Nitro-3-Phenylpyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. This compound matters because it serves as a critical precursor for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the introduction of specific chloro, nitro, and phenyl functionalities into complex molecular architectures. Pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical companies need this intermediate for creating new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor programs and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the pyridine core provides specific bioactivity.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, ligands for catalysis, and functional polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific halogenated nitropyridine scaffold.

Basic Information

Product Name	2-Chloro-5-Nitro-3-Phenylpyridine
CAS No.	1119088-46-8
Molecular Formula	C11H7ClN2O2
Molecular Weight	234.64 g/mol
Synonyms	3-Phenyl-2-chloro-5-nitropyridine; 2-Chloro-3-phenyl-5-nitropyridine; 5-Nitro-2-chloro-3-phenylpyridine; Pyridine, 2-chloro-5-nitro-3-phenyl-; (2-Chloro-5-nitro-3-pyridinyl)benzene
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Nitro-3-Phenylpyridine is manufactured under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and tendency to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the original container has been opened.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.