Description

Methyl 6-Chloro-5-(Chlorosulfonyl)Pyridine-3-Carboxylate is a high-value, multi-functional pyridine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique bifunctional structure, featuring both a chlorosulfonyl and a methyl ester group, makes it an essential building block for constructing complex molecules with targeted properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, infectious diseases, and metabolic disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the pyridine core provides bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its reactive handles.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Methyl 6-Chloro-5-(Chlorosulfonyl)Pyridine-3-Carboxylate
CAS No.	1118787-95-3
Molecular Formula	C7H5Cl2NO4S
Molecular Weight	270.09 g/mol
Synonyms	6-Chloro-5-(chlorosulfonyl)nicotinic acid methyl ester; Methyl 6-chloro-5-chlorosulfonylnicotinate; 3-Pyridinecarboxylic acid, 6-chloro-5-(chlorosulfonyl)-, methyl ester; Methyl 6-chloro-5-(sulfonyl chloride)nicotinate; 5-(Chlorosulfonyl)-6-chloropyridine-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Chloro-5-(Chlorosulfonyl)Pyridine-3-Carboxylate adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, GC, and NMR to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.