Description

4-Bromo-3-Methyl-1-Tosyl-1H-Pyrazole is a high-purity, functionalized pyrazole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the combination of a reactive bromine atom and a tosyl-protected nitrogen, enabling precise, multi-step molecular construction for complex target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting kinase inhibition or other heterocycle-dependent biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the pyrazole core is a common bioactive motif.
• Material Science Chemistry: Serves as a precursor for creating specialized ligands, organic semiconductors, or photoactive materials.
• Cross-Coupling Reactions: The bromine substituent makes it a suitable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Chemical Biology & Proteomics: Can be utilized as a scaffold for developing molecular probes or activity-based protein profiling agents.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Bromo-3-Methyl-1-Tosyl-1H-Pyrazole
CAS No.	1116093-49-2
Molecular Formula	C11H11BrN2O2S
Molecular Weight	315.19 g/mol
Synonyms	1H-Pyrazole, 4-bromo-3-methyl-1-[(4-methylphenyl)sulfonyl]-; 4-Bromo-3-methyl-1-(p-tolylsulfonyl)-1H-pyrazole; 4-Bromo-3-methyl-1-tosylpyrazole; 4-Bromo-3-methyl-1-(4-methylbenzenesulfonyl)-1H-pyrazole; 1-Tosyl-4-bromo-3-methylpyrazole; 4-Bromo-3-methyl-1-(tosyl)pyrazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Methyl-1-Tosyl-1H-Pyrazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced applications and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.