Description

5-Bromo-1-(cyclopropylmethyl)pyridin-2(1H)-one is a high-purity brominated pyridone derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its value lies in providing a versatile halogenated scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small molecule therapeutics, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its halogenated heterocyclic structure.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways.
• Material Science: Serves as a precursor for functionalized organic molecules used in advanced materials, such as organic semiconductors or ligands for catalysis.
• Contract Research & Development (CRO/CDMO): Supplied to outsourcing partners for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional laboratories for methodological studies in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	5-Bromo-1-(cyclopropylmethyl)pyridin-2(1H)-one
CAS No.	1114573-41-9
Molecular Formula	C9H10BrNO
Molecular Weight	228.09 g/mol
Synonyms	5-Bromo-1-(cyclopropylmethyl)-2(1H)-pyridinone; 5-Bromo-1-(cyclopropylmethyl)-1,2-dihydropyridin-2-one; 5-Bromo-1-(cyclopropylmethyl)pyridin-2-one; 2(1H)-Pyridinone, 5-bromo-1-(cyclopropylmethyl)-; 5-Bromo-1-(cyclopropylmethyl)-2-pyridone; 1-(Cyclopropylmethyl)-5-bromopyridin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-(cyclopropylmethyl)pyridin-2(1H)-one is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.