Description

5-Bromo-1-(2,2,2-trifluoroethyl)pyridin-2(1H)-one is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a bromine substituent and a trifluoroethyl group, which provides a versatile handle for further functionalization and introduces desirable physicochemical properties into target molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically relevant heterocycles.
• Agrochemical Research: Used in the synthesis of advanced pesticide and herbicide molecules, where the trifluoromethyl group can enhance metabolic stability and lipophilicity.
• Material Science Precursor: Serves as a specialized monomer or building block for developing functional polymers and advanced organic electronic materials.
• Chemical Biology Probe Development: Employed to create tagged or modified molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-Bromo-1-(2,2,2-trifluoroethyl)pyridin-2(1H)-one
CAS No.	1114563-10-8
Molecular Formula	C7H5BrF3NO
Molecular Weight	256.02 g/mol
Synonyms	5-Bromo-1-(2,2,2-trifluoroethyl)-2(1H)-pyridinone; 5-Bromo-1-(2,2,2-trifluoroethyl)pyridin-2-one; 2(1H)-Pyridinone, 5-bromo-1-(2,2,2-trifluoroethyl)-; 5-Bromo-1-(trifluoroethyl)-2-pyridone; 5-Bromo-1-(2,2,2-trifluoroethyl)-1,2-dihydropyridin-2-one
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-(2,2,2-trifluoroethyl)pyridin-2(1H)-one is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality ensures reliable performance in your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.