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1-(2-Bromo-5-Fluoropyridin-4-Yl)Ethan-1-Ol CAS NO 1114523-54-4


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CAS No.:1114523-54-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(2-Bromo-5-Fluoropyridin-4-Yl)Ethan-1-Ol is a high-value fluorinated pyridine derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring both bromo and fluoro substituents on the pyridine ring, makes it indispensable for constructing complex molecules with precise electronic and steric properties. This compound is primarily sought after by pharmaceutical and agrochemical research & development teams for the synthesis of novel active ingredients, including potential kinase inhibitors and other biologically relevant heterocycles.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for targeted therapies and kinase inhibitors.
  • Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluoropyridine moiety enhances bioavailability and stability.
  • Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
  • Chemical Biology Probes: Serves as a building block for creating molecular probes to study biological pathways and protein functions.
  • Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name 1-(2-Bromo-5-Fluoropyridin-4-Yl)Ethan-1-Ol
CAS No. 1114523-54-4
Molecular Formula C7H7BrFNO
Molecular Weight 220.04 g/mol
Synonyms 1-(2-Bromo-5-fluoropyridin-4-yl)ethanol; 1-(2-Bromo-5-fluoro-4-pyridinyl)ethanol; 4-Pyridineethanol, 2-bromo-5-fluoro-; 2-Bromo-5-fluoro-4-(1-hydroxyethyl)pyridine; α-(2-Bromo-5-fluoropyridin-4-yl)ethanol; (2-Bromo-5-fluoropyridin-4-yl)methanol (common misnomer, verify structure); 1-(2-Bromo-5-fluoro-4-pyridyl)ethan-1-ol
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Quality Control

Our production of 1-(2-Bromo-5-Fluoropyridin-4-Yl)Ethan-1-Ol adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality system is designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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