Description

2-Chloro-3-Trifluoromethylpyridine-5-Carboxaldehyde is a high-value, multi-functional pyridine derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both chloro and trifluoromethyl substituents on the pyridine ring, makes it an indispensable building block for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, insecticides, and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing specialized ligands used in catalysis and material science.
• Functional Material Research: Employed in the creation of organic electronic materials, liquid crystals, and advanced polymers.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Chloro-3-Trifluoromethylpyridine-5-Carboxaldehyde
CAS No.	1113049-90-3
Molecular Formula	C7H3ClF3NO
Molecular Weight	209.55 g/mol
Synonyms	5-Formyl-2-chloro-3-(trifluoromethyl)pyridine; 2-Chloro-3-(trifluoromethyl)pyridine-5-carbaldehyde; 2-Chloro-3-trifluoromethyl-5-pyridinecarboxaldehyde; 2-Chloro-3-trifluoromethyl-5-formylpyridine; 2-Chloro-α,α,α-trifluoro-5-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-Trifluoromethylpyridine-5-Carboxaldehyde is produced and tested under a strict quality management system. We guarantee high-purity material suitable for demanding R&D and scale-up applications. Comprehensive analytical testing, including HPLC, GC, NMR, and MS, is performed to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.