Description

tert-Butyl2-(3-Formylbicyclo[1.1.1]pentan-1-yl)acetate is a high-value, functionalized bicyclic building block designed for advanced synthetic chemistry. This compound matters because its unique, rigid [1.1.1]propellane-derived core and aldehyde functionality enable the efficient construction of complex, three-dimensional molecular architectures, which are highly sought after in modern drug discovery. Pharmaceutical and agrochemical R&D teams need it to develop novel active ingredients with improved potency and selectivity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disease targets, leveraging its three-dimensional scaffold.
• Agrochemical Synthesis: Used to create advanced pesticide and herbicide molecules with novel modes of action and enhanced environmental profiles.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique mechanical or optical properties.
• Chemical Biology Probes: Employed in the design of molecular probes and tools for studying biological pathways and protein interactions.
• Ligand and Catalyst Development: Utilized for constructing sophisticated ligand frameworks in asymmetric catalysis and organometallic chemistry.

Basic Information

Product Name	tert-Butyl2-(3-Formylbicyclo[1.1.1]pentan-1-yl)acetate
CAS No.	1113001-80-1
Molecular Formula	C12H18O3
Molecular Weight	210.27 g/mol
Synonyms	1-(tert-Butoxycarbonylmethyl)-3-formylbicyclo[1.1.1]pentane; tert-Butyl (3-formylbicyclo[1.1.1]pentan-1-yl)acetate; 3-Formylbicyclo[1.1.1]pentane-1-acetic acid tert-butyl ester; Bicyclo[1.1.1]pentane-1-acetic acid, 3-formyl-, 1,1-dimethylethyl ester; BCP-CH2-COOtBu-CHO
EINECS	Contact for details

Quality Control

Our production of tert-Butyl2-(3-Formylbicyclo[1.1.1]pentan-1-yl)acetate adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity, the container should be kept tightly sealed after each use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.